- The O'Jays
- Oasis
- Obituary
- Obliteration
- Oddisee
- Odesza
- Odesza & Yellow House
- Odetta
- Of Monsters And Men
- Of Montreal
- OFF!
- The Offspring
- Ohio Players
- Oingo Boingo
- Oki
- Okkervil River
- Okyerema Asante
- Ol' Dirty Bastard
- Old Crow Medicine Show
- Old Man Luedecke
- Oliver Nelson
- Oliver Sim
- Olivia Dean
- Olivia Rodrigo
- The Olivia Tremor Control
- Oluko Imo
- The Olympians
- OM
- Omar Khorshid
- Omar Khorshid And His Group
- Omar Souleyman
- Omnipotence
- Omodaka
- One Last Wish
- One Way System
- Oneida
- Oneness Of Juju
- Oneohtrix Point Never
- Onipa
- Onyx
- Oozing Wound
- Open Mike Eagle
- Operation Ivy
- Operators
- Opeth
- Optimistics
- Orange Goblin
- Orchestral Manoeuvres In The Dark
- The Organ
- The Orlando Julius With Heliocentrics
- Ornette Coleman
- The Ornette Coleman Double Quartet
- The Ornette Coleman Quartet
- Orquesta Akokán
- Orquesta Akokán Canta: Jose "Pepito" Gomez
- Orquesta De Las Nubes
- Orville Peck
- Os Mutantes
- Oscar Peterson
- The Oscar Peterson Trio
- Oscar Peterson Trio The Milt Jackson
- Osiris
- The Other People Place
- Otis Clay
- Otis Redding
- Otis Redding & Carla Thomas
- Otis Rush
- Otis Spann
- Otis Spann with Fleetwood Mac
- Otto Kentrol Feat. Faceless
- Otto Klemperer Philharmonia Chorus Philharmonia Orchestra Felix Mendelssohn-Bartholdy
- Our Lady Peace
- The Outcasts
- OutKast
- Oval
- Overkill
- Overmono
- Ozzy Osbourne
- Suzie Ungerleider
- Ólafur Arnalds
- Ô Paon